benzoic acid, 4-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]amino]-
4-cinnamamidobenzoic acid
CAS: 54057-59-9
Molecular Formula: C16H13NO3
benzoic acid, 4-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]amino]- - Names and Identifiers
| Name | 4-cinnamamidobenzoic acid |
| Synonyms | 4-CINNAMAMIDOBENZOIC ACID 4-cinnamamidobenzoic acid 4-[(1-oxo-3-phenylprop-2-enyl)amino]benzoic acid 4-{[(2E)-3-phenylprop-2-enoyl]amino}benzoic acid Benzoic acid, 4-[(1-oxo-3-phenyl-2-propen-1-yl)amino]- benzoic acid, 4-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]amino]- |
| CAS | 54057-59-9 |
| InChI | InChI=1/C16H13NO3/c18-15(11-6-12-4-2-1-3-5-12)17-14-9-7-13(8-10-14)16(19)20/h1-11H,(H,17,18)(H,19,20)/b11-6+ |
benzoic acid, 4-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]amino]- - Physico-chemical Properties
| Molecular Formula | C16H13NO3 |
| Molar Mass | 267.28 |
| Density | 1.31g/cm3 |
| Boling Point | 538.1°C at 760 mmHg |
| Flash Point | 279.2°C |
| Vapor Presure | 2.08E-12mmHg at 25°C |
| Refractive Index | 1.693 |
benzoic acid, 4-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]amino]- - Introduction
4-cinnamidobenzoic acid is an organic compound with a chemical formula of C16H13NO2 and a molecular weight of 263.28g/mol.
Nature:
4-cinnamamidobenzoic acid is a white crystalline solid, soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide, and slightly soluble in water. Its melting point is about 183-185 degrees Celsius.
Use:
4-cinnamidobenzoic acid is commonly used as an intermediate in organic synthesis. It can be used to synthesize biologically active compounds such as drugs and dyes. In addition, it can also be used in the preparation of coatings and plastic additives.
Preparation Method:
Under normal circumstances, the preparation method of 4-cinnamidobenzoic acid is to react benzoic acid and cinnamoyl chloride, and then add ammonia to react to obtain the product. The specific reaction conditions can be adjusted according to the experimental requirements.
Safety Information:
4-cinnamidobenzoic acid has no obvious toxicity to human health. However, like many organic compounds, it can cause irritation to the eyes, skin and respiratory tract. When using, wear protective glasses and gloves, and ensure that the operation is carried out in a well-ventilated laboratory. Avoid inhaling its dust or solution during processing, and avoid contact with open flames or high temperature sources. If contact occurs, immediately flush the affected area with plenty of water and seek medical help if needed.
Nature:
4-cinnamamidobenzoic acid is a white crystalline solid, soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide, and slightly soluble in water. Its melting point is about 183-185 degrees Celsius.
Use:
4-cinnamidobenzoic acid is commonly used as an intermediate in organic synthesis. It can be used to synthesize biologically active compounds such as drugs and dyes. In addition, it can also be used in the preparation of coatings and plastic additives.
Preparation Method:
Under normal circumstances, the preparation method of 4-cinnamidobenzoic acid is to react benzoic acid and cinnamoyl chloride, and then add ammonia to react to obtain the product. The specific reaction conditions can be adjusted according to the experimental requirements.
Safety Information:
4-cinnamidobenzoic acid has no obvious toxicity to human health. However, like many organic compounds, it can cause irritation to the eyes, skin and respiratory tract. When using, wear protective glasses and gloves, and ensure that the operation is carried out in a well-ventilated laboratory. Avoid inhaling its dust or solution during processing, and avoid contact with open flames or high temperature sources. If contact occurs, immediately flush the affected area with plenty of water and seek medical help if needed.
Last Update：2024-04-09 20:52:54
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